Question 1

What is Type I borosilicate glass?

Accepted Answer

Type I borosilicate is the most chemically resistant glass used in pharmaceutical primary packaging. Its low alkali content and high hydrolytic resistance make it suitable for injectable products that are sensitive to leachables, pH shift or delamination. KAISHA Pharma manufactures its ampoules, vials, cartridges and prefilled syringes in Type I borosilicate glass.

Question 2

What is the difference between ready-to-fill (RTF) and ready-to-sterilize (RTS) vials?

Accepted Answer

Ready-to-fill vials arrive washed, depyrogenated and sterilised, packed in nested tubs or trays so they can go straight onto an aseptic filling line. Ready-to-sterilize vials arrive washed and packed but are sterilised by the customer before filling. RTF removes washing and sterilisation steps from the fill-finish operation; RTS keeps that control in-house.

Question 3

What sizes of glass ampoules does KAISHA Pharma manufacture?

Accepted Answer

KAISHA Pharma manufactures Form B, Form C and Form D pharmaceutical glass ampoules from 1 ml to 30 ml, in clear or amber Type I borosilicate glass. Standard sizes are 1, 2, 3, 5, 10, 20 and 30 ml, with custom sizes available on request.

Question 4

What size range of pharmaceutical glass vials is available?

Accepted Answer

KAISHA Pharma supplies crimp neck vials from 1 ml to 100 ml and screw neck vials from 1 ml to 50 ml. Both are available in bulk, sterile, ready-to-sterilize and ready-to-fill nested configurations, in clear or amber glass.

Question 5

What is a nested vial tub?

Accepted Answer

A nested tub holds pre-sterilised vials in a moulded plastic nest inside a sealed tub, so containers arrive pre-positioned for automated filling. The nest keeps each container separated and correctly oriented, which reduces glass-to-glass contact, cosmetic defects and line changeover time.

Question 6

What is siliconization in prefilled syringes?

Accepted Answer

Siliconization is the controlled application of silicone oil to the inside of a syringe barrel so the plunger moves smoothly and delivery force stays consistent. KAISHA Pharma applies silicone through an automated process designed for uniform coverage, with dedicated inspection technologies verifying silicone presence during production.

Question 7

What is a lyophilization bottom vial?

Accepted Answer

A lyophilization bottom vial has a modified, flatter base profile that improves thermal contact with the freeze-dryer shelf. Better heat transfer supports more uniform freeze-drying across a batch. KAISHA Pharma offers a lyophilization bottom as a feature option across its vial range.

Question 8

What is a one point cut (OPC) ampoule?

Accepted Answer

A one point cut ampoule carries a single scored break point below the neck, with a coloured break ring identifying it. The score concentrates the break at one location so the ampoule opens cleanly and consistently, reducing glass particulate and the force required to open it.

Question 9

What is the difference between ETO and gamma sterilisation?

Accepted Answer

Ethylene oxide (ETO) sterilisation uses a chemical gas cycle at low temperature, suitable for assembled devices and moisture-sensitive components. Gamma sterilisation uses ionising radiation and requires no aeration period. KAISHA Pharma operates in-house ETO sterilisation and also supplies gamma-sterilised syringes and cartridges.

Question 10

Does KAISHA Pharma supply amber glass containers?

Accepted Answer

Yes. Amber glass is available across the ampoule and vial ranges, and for cartridge bottles. Amber glass filters ultraviolet light and is used for light-sensitive drug products where photostability is a formulation concern.

Question 11

Who is KAISHA Pharma?

Accepted Answer

KAISHA Pharma is a pharmaceutical primary glass packaging manufacturer and a Dadachanji Group company. It began in 1990 manufacturing glass ampoules and today operates a 300,000 sq. ft. manufacturing facility on a 25-acre campus, producing ampoules, vials, cartridges and prefilled syringes for injectable pharmaceuticals.

Question 12

What makes KAISHA Pharma different from other glass packaging suppliers?

Accepted Answer

KAISHA Pharma sits inside the Dadachanji Group, which also develops formulations and manufactures injectables through Sovereign Pharma and KAISHA Lifesciences. That means the container is designed by a group that also runs fill-finish operations — an understanding of the filling line that a standalone packaging vendor does not have.

Solutions for every injectable format.

Four formats. One standard.

Glass Ampoules

Glass Vials

Prefilled Syringes

Glass Cartridges

Completing the delivery system.

Sycure AD

Sycure TE

Plunger Rods

Backstops & Finger Grips

Designed around flexibility.
Built for every stage of manufacturing.